PUBLICATIONS

J. Lin, N. Sanz del Olmo, J. San Jacinto Garcia, F. Namata, D. J. Hutchinson, M. Malkoch. “Impact of Polyester Dendrimers as Branched Multifunctional Cross-Linking Additives in Triazine-Trione-Based Composites Developed via High-Energy Visible Light Thiol–ene Chemistry” ACS Applied Polymer Materials, 2023, 5, 10395. (doi: 10.1021/acsapm.3c02246)

G. Patt-Lafitte, O. Valfort, D. J. Hutchinson, M. Malkoch, D. Eglin. ” Toughening and strengthening of visible light-cured hydroxyapatite thiol-ene resin composite intended as bone fixation using 2D textile” Journal of Materials Research and Technology, 2024, 29, 982. (doi: 10.1016/j.jmrt.2024.01.127)

N. Sanz del Olmo, N. Molina, Y. Fan, F. Namata, D. J. Hutchinson, M. Malkoch. ”Antibacterial Hydrogel Adhesives Based on Bifunctional Telechelic Dendritic-Linear−Dendritic Block Copolymers” J. Am. Chem. Soc. 2024, 146, 17240. (doi: 10.1021/jacs.4c03673)

J. San Jacinto Garcia, N. Sanz del Olmo, D. J. Hutchinson, M. Malkoch. “Enhanced Degradability of Thiol–Ene Composites through the Inclusion of Isosorbide-Based Polycarbonates” ACS Applied Materials & Interfaces, 2024, 16, 40056. (doi: 10.1021/acsami.4c09626)

P. Schwarzenberg, T. Colding-Rasmussen, D. J. Hutchinson, D. Mischler, P. Horstmann, M. M. Petersen, S. Jacobsen, T. Pastor, M. Malkoch, C. Wong, P. Varga. ”Biomechanical performance of a novel light‑curable bone fixation technique” Scientific Reports, 2023, 13, 9339. (doi: 10.1038/s41598-023-35706-3)

T. Colding-Rasmussen, P. Schwarzenberg, P. F. Horstmann, C. B. S. Ottesen, J. S. J. Garcia, D. J. Hutchinson, M. Malkoch, M. M. Petersen, P. Varga, C. N. E. Tierp-Wong. “Biomechanical Variability and Usability of a Novel Customizable Fracture Fixation Technique“ Bioengineering, 2023, 10, 1146. (doi:10.3390/bioengineering10101146)

F. Namata, N. Sanz del Olmo, N. Molina, M. Malkoch. “Synthesis and Characterization of Amino-Functional Polyester Dendrimers Based On Bis-MPA with Enhanced Hydrolytic Stability and Inherent Antibacterial Properties” Biomacromolecules, 2023, 24, 858. (doi: 10.1021/acs.biomac.2c01286)

J. Lin, Y. Fan, D. J. Hutchinson, M. Malkoch. “Soft Hydroxyapatite Composites Based on Triazine–Trione Systems as Potential” Biomedical Engineering Frameworks ACS Applied Materials and Interfaces, 2023, 15, 7329. (doi: 10.1021/acsami.2c16235)

M. Ovesy, J. D. Silva-Henao, J.W.A Fletcher, B. Gueorguiev, P.K. Zysset, P. Varga. “Non-linear explicit micro-FE models accurately predict axial pull-out force of cortical screws in human tibial cortical bone” J Mech Behav Biomed Mater. 2022 Feb;126:105002. (doi: 10.1016/j.jmbbm.2021.105002)

I. Zderic, P. Varga, U. Styger, L. Drenchev, B. Gueorguiev, E. Asimus, W.B. Saunders, M. Kowaleski, R. J. Boudrieau, L. M. Dejardin “Mechanical Evaluation of Two Hybrid Locking Plate Designs for Canine Pancarpal Arthrodesis” Biomed Res Int. 2021 Sep 2;2021:2526879  (doi: 10.1155/2021/2526879).

P. Stenström, Y. Fan, Y. Zhang, D. Hutchinson, S. García-Gallego, M. Malkoch, ”UV-Cured Antibacterial Hydrogels Based on PEG and Monodisperse Hetereofunctional Bis-MPA Dendrimers” Molecules 2021, 26, 2364 (doi: 10.3390/molecules26082364).

G. S. Lewis, D.  Mischler, H. Wee, J. S. Reid, P. Varga, “Finite Element Analysis of Fracture Fixation” Curr Osteoporos” Rep. 2021 Aug;19(4):403-416 (doi: 10.1007/s11914-021-00690-y).

M. Lenz, P. Varga, D. Mischler, B. Gueorguiev, K. Klos, A. Fernandez dell'Oca, P. Regazzoni , R. G. Richards, S. M. Perren. “Helical plating - a novel technique to increase stiffness in defect fractures” Eur Cell Mater. 2021 Aug 19;42:110-121 (doi: 10.22203/eCM.v042a08).

J. F. Schader, D. Mischler, J. Dauwe, R. G. Richards, B. Gueorguiev, P. Varga. “One size may not fit all: patient-specific computational optimization of locking plates for improved proximal humerus fracture fixation” J Shoulder Elbow Surg. 2022 Jan;31(1):192-200 (doi: 10.1016/j.jse.2021.06.012).

D. J. Hutchinson, V. Granskog, J. von Kieseritzky, H. Alfort, P. Stenlund, Y. Zhang, M. Arner, J. Håkansson, M. Malkoch, ”Highly Customizable Bone Fracture Fixation through the Marriage of Composites and Screws” Adv. Funct. Mater. 2021, 2105187 (doi: 10.1002/adfm.202105187).

Y. Fan, S. Mohanty, Y. Zhang, M. Lüchow, L. Qin, L. Fortuin, A. Brauner, M. Malkoch, ”Dendritic Hydrogels Induce Immune Modulation in Human Keratinocytes and effectively Eradicate Bacterial Pathogens” J. Am. Chem. Soc. 2021, 143, 17180 (doi: 10.1021/jacs.1c07492).

P. Schwarzenberg, K. Klein, S. J. Ferguson, B. von Rechenberg, S. Darwiche, H. L. Dailey “Virtual mechanical tests out-perform morphometric measures for assessment of mechanical stability of fracture healing in vivo” J Orthop Res. 2021 Apr;39(4):727-738. doi: 10.1002/jor.24866.

J. von Kieseritzky, H. Alfort, V. Granskog, D. Hutchinson, P. Stenlund, Y. Bogestål, M. Arner, J. Håkansson, M. Malkoch, ”DendroPrime as an adhesion barrier on fracture fixation plates: an experimental study in rabbits” J. Hand Surg. (Eur.) 2020, 45, 742 (doi: 10.1177/1753193420932477).

D. Mischler, S. Babu, G. Osterhoff, C. Pari, J. Fletcher, M. Windolf, B. Gueorguiev, P. Varga “Comparison of optimal screw configurations in two locking plate systems for proximal humerus fixation - a finite element analysis study” Clin Biomech (Bristol, Avon). 2020 Aug;78:105097 (doi: 10.1016/j.clinbiomech.2020.105097).

S. García-Gallego, P. Stenström, P. Mesa-Antunez, Y. Zhang, M. Malkoch, ”Synthesis of Heterofunctional Polyester Dendrimers with Internal and External Functionalities as Versatile Multipurpose Platforms” Biomacromol. 2020, 21, 4273 (doi: 10.1021/acs.biomac.0c01068).

P. Schwarzenberg, S. Darwiche, R. S. Yoon, H. L. Dailey HL  “Imaging Modalities to Assess Fracture Healing” Curr Osteoporos Rep. 2020 Jun;18(3):169-179. doi: 10.1007/s11914-020-00584-5.

Y. Fan, M. Lüchow, Y. Zhang, J. Lin, L. Fortuin, S. Mohanty, A. Brauner, M. Malkoch, “Nanogel Encapsulated Hydrogels As Advanced Wound Dressings for the Controlled Delivery of Antibiotics” Adv. Funct. Mater. 2020, 2006453 (doi: 10.1002/adfm.202006453).

O. C. J. Andrén, T. Ingverud, D. Hult, J. Håkansson, Y. Bogestål, J. S. Caous, K. Blom, Y. Zhang, T. Andersson, E. Pedersen, C. Björn, P. Löwerhielm, M. Malkoch, “Antibiotic-Free Cationic Dendritic Hydrogels as Surgical-Site-Infection-Inhibiting Coatings” Adv. Healthcare Mater. 2019, 1801619 (doi: 10.1002/adhm.201801619).

M. Ojansivu, A. Rashad, A. E. Ahlinder, J. Massera, A. Mishra, K. Syverud, A. Finne-Wistrand, S. Miettinen, K. Mustafa, “Wood-Based Nanocellulose and Bioactive Glass Modified Gelatin-Alginate Bioinks for 3D Bioprinting of Bone Cells” Biofabrication, 2019, 11, 035010 (doi: 10.1088/1758-5090/ab0692).

A. Bersellini Farinotti, G. Wigerblad, D. Nascimento, D. B. Bas, C. Morado Urbina, K. S. Nandakumar, K. Sandor, B. Xu, S. Abdelmoaty, M. Hunt, K. Ängeby Möller, A. Baharpoor, J. Sinclair, K. Jardemark, J. T. Lanner, I. Khmaladze, L. E. Borm, L. Zhang, F. Wermeling, M. Cragg, A. J. Chabot-Doré, L. Diachenko, I. Belfer, M. Collin, K. Kultima, B. Heyman, J. M. Andrade Jimenez, S. Codeluppi, R. Holmdahl, C. I. Svensson, “Cartilage-binding antibodies induce pain through immune complex mediated stimulation of neurons” J. Exp Med. 2019, 216, 1904-1924 (doi: 10.1084/jem.20181657).

Y. Lai, Y. Li, H. Cao, J. Long, X. Wang, L. Li, C. Li, Q. Jia, B. Teng, T. Tang, J. Peng, D. Eglin, M. Alini, D. W. Grijpma, G. Richards, L. Quin, “Osteogenic magnesium incorporated into PLGA/TCP porous scaffold by 3D printing for repairing challenging bone defect” Biomaterials, 2019, 197, 207-219 (doi: 10.1016/j.biomaterials.2019.01.013).

P. Schwarzenberg, M. M. Maher, J. A. Harty, H. L. Dailey “Virtual structural analysis of tibial fracture healing from low-dose clinical CT scans” J Biomech. 2019 Jan 23;83:49-56. doi: 10.1016/j.jbiomech.2018.11.020.

H. L. Dailey, P. Schwarzenberg, C. J. Daly, S. A. M. Boran, M. M. Maher MM, J. A. Harty “Virtual Mechanical Testing Based on Low-Dose Computed Tomography Scans for Tibial Fracture: A Pilot Study of Prediction of Time to Union and Comparison with Subjective Outcomes Scoring” J Bone Joint Surg Am. 2019 Jul 3;101(13):1193-1202. doi: 10.2106/JBJS.18.01139.

D. Ciric, D. Mischler, F. Qawasmi, L. Wenzel, R. G. Richards, B. Gueorguiev, M. Windolf, P. Varga “Secondary Perforation Risk in Plate Osteosynthesis of Unstable Proximal Humerus Fractures: A Biomechanical Investigation of the Effect of Screw Length” J Orthop Res. 2019 Dec;37(12):2625-2633. doi: 10.1002/jor.24429.

J. W. A. Fletcher, M. Windolf, R. G. Richards, B. Gueorguiev, P. Varga “Screw configuration in proximal humerus plating has a significant impact on fixation failure risk predicted by finite element models” J Shoulder Elbow Surg. 2019 Sep;28(9):1816-1823 (doi: 10.1016/j.jse.2019.02.013).

V. Granksog, S. García-Gallego, J. von Kieseritzky, J. Rosendahl, P. Stenlund, Y. Zhang, S. Petronis, B. Lyvén, M. Arner, J. Håkansson, M. Malkoch, “High-Performance Thiol-Ene Composites Unveil a New Era of Adhesives Suited for Bone Repair” Adv. Funct. Mater. 2018, 28, 1800372 (doi: 10.1002/adfm.201800372).

D. Hult, S. García-Gallego, T. Ingverud, O. C. J. Andrén, M. Malkoch, “Degradable high Tg sugar-derived polycarbonates from isosorbide and dihydroxyacetone” Polym. Chem. 2018, 9, 2238-2246 (doi: 10.1039/c8py00256h).

M. Arseneault, V. Granskog, S. Khosravi, I. M. Heckler, P. Mesa-Antunez, D. Hult, Y. Zhang, M. Malkoch, “The Dawn of Thiol-Yne Triazine Triones Thermosets as a New Material Platform Suited for Hard Tissue Repair” Adv. Mater. 2018, 1804966 (doi: 10.1002/adma.201804966).

C. Gjerde, K. Mustafa, S. Hellem, M. Rojewski, H. Gjengedal, M. A. Yassin, X. Feng, S. Skaale, T. Berge, A. Rosen, X. Q. Shi, A. B. Ahmed, B. T. Gjertsen, H. Schrezenmeier, P. Layrolle, “Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial” Stem Cell Res. Ther. 2018, 9, 213 (doi: 10.1186/s13287-018-0951-9).

S. Sharma, D. Sapkota, Y. Xue, S. Rajthala, M. Yassin, A. Finne-Wistrand, K. Mustafa, “Delivery of VEGFA in bone marrow stromal cells seeded in copolymer scaffold enhances angiogenesis, but is inadequate for osteogenesis as compared with the dual delivery of VEGFA and BMP2 in a subcutaneous mouse model” Stem Cell Res. Ther. 2018, 9, 23 (doi: 10.1186/s13287-018-0778-4).

N. Bjørslev, L. B. Ebskov, C. Mersø, C. Wong, “Complications and patient-injury after ankle fracture surgery. –A closed claim analysis with data from the Patient Compensation Association in Denmark” Injury, 2018, 49, 430-436 (doi: 10.1016/j.injury.2017.11.025).

K. Sandor, S. Krishnan, N. A. Agalave, J. Villarreal Salcido, T. Fernandez Zafra, P. Pemami Khoonsari, C. I. Svensson, K. Kultima, “Spinal injection of newly identified cerebellin-1 and cerebellin-2 peptides induce mechanical hypersensitivity in mice” Neuropeptides. 2018, 69, 53-59 (doi: 10.1016/j.npep.2018.04.004).

J. J. Bara, I. Dresing, S. Zeiter, M. Anton, G. Daculsi, D. Eglin, D. Nehrbass, V. A. Stadelmann, D. C. Betts, R. Müller, M. Alini, M. J. Stoddart, “A doxycycline inducible, adenoviral bone morphogenetic protein-2 gene delivery system to bone” J. Tissue Eng. Regen. Med. 2018, e106-e118 (doi: 10.1002/term.2393).

P. Varga, L. Grünwald, J.A. Inzana, M. Windolf. "Fatigue failure of plated osteoporotic proximal humerus fractures is predicted by the strain around the proximal screws" Journal of the Mechanical Behavior of Biomedical Materials, 2017, 75, 68-74.

S, Suliman, Y. Sun, T. O. Pedersen, Y. Xue, J. Nickel, T. Waag, H. Lygre, A. Finne-Wistrand, D. Steinmüller-Nethl, A. Krueger, D. Costea, K. Mustafa, “In vivo host response and degradation of copolymer scaffolds functionalized with nanodiamonds and bone morphogenetic protein 2” Adv. Healthcare Mater. 2016, 5, 730-742 (doi: 10.1002/adhm.201500723).

Y.P. Acklin, I. Zderic, J. Buschbaum, P. Varga, J.A. Inzana, S. Grechenig, R.G. Richards, B. Gueorguiev, P. Schmitz. "Biomechanical comparison of plate and screw fixation in anterior pelvic ring fractures with low bone mineral density." Injury, 2016, 47, 1456-1460.

G. Wigerblad, D. B. Bas, C. Fernades-Cerqueira, A. Krishnamurthy, K. S. Nandakumar, J. Kato, K. Sandor, J. Su, A. Finn, A. Bersellini Farinotti, K. Amara, K. Lundberg, R. Holmdahl, P. J. Jakobsson, V. Malmström, A. I. Catrina, L. Klareskog, C. I. Svensson, “Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism” Ann. Rheum Dis. 2016, 75, 730-738 (doi: 10.1136/annrheumdis-2015-208094).

V. Leeberg, S. Sonne-Holm, J. Krogh Christoffersen, C. Wong, “Fractures of the knee in children – what can go wrong? A case file study of closed claims in The Patient Compensation Association covering 16 years” J. Child.’s Orthop. 2015, 9, 391-396.